RORC anticorps (N-Term)

N° du produit ABIN2787955

Cet anticorps Lapin Polyclonal détecte spécifiquement RORC dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Cheval, Cobaye, Chien, Lapin, Porc, Chévre, Mouton et Poisson zèbre (Danio rerio).

Aperçu rapide pour RORC anticorps (N-Term) (ABIN2787955)

Antigène: RORC (RAR-Related Orphan Receptor C (RORC))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Cobaye, Chien, Lapin, Porc, Chévre, Mouton, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RORC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-RORC anticorps

Épitope: N-Term

Séquence: KICGDKSSGI HYGVITCEGC KGFFRRSQRC NAAYSCTRQQ NCPIDRTSRN

Homologie: Cow: 86%, Dog: 79%, Goat: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 79%, Rat: 86%, Sheep: 79%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against RORC. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RORC

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 497 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RORC

Antigène: RORC (RAR-Related Orphan Receptor C (RORC))

Autre désignation: RORC

Sujet: RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC129539, NR1F3, RORG, RZR-GAMMA, RZRG, TOR
Protein Interaction Partner: EVI2A, NCOA6, EIF3I, CHD4, EIF4EBP1,
Protein Size: 497

Poids moléculaire: 56 kDa

ID gène: 6097

NCBI Accession: NM_001001523, NP_001001523

UniProt: B3KUU9

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway