alpha 2 Macroglobulin anticorps (N-Term)

N° du produit ABIN2787981

Détail du produit anti-alpha 2 Macroglobulin anticorps

Antigène: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha 2 Macroglobulin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: PVPGHVTVSI CRKYSDASDC HGEDSQAFCE KFSGQLNSHG CFYQQVKTKV

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against A2M. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1474 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur alpha 2 Macroglobulin

Antigène: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Autre désignation: A2M (A2M Produits)

Synonymes: anticorps A2MD, anticorps CPAMD5, anticorps FWP007, anticorps S863-7, anticorps A2MAC1, anticorps A2m1, anticorps A2maa, anticorps Mam, anticorps A2mp, anticorps A2M, anticorps LOC733429, anticorps endod, anticorps cpamd5, anticorps fwp007, anticorps s863-7, anticorps a2mb, anticorps endodermin, anticorps Alpha-2-M, anticorps alpha-2-macroglobulin, anticorps pregnancy-zone protein L homeolog, anticorps alpha-2-macroglobulin S homeolog, anticorps pregnancy zone protein, anticorps alpha-2-macroglobulin-like, anticorps A2M, anticorps A2m, anticorps LOC477699, anticorps pzp.L, anticorps AZL_c00450, anticorps LOC100349077, anticorps a2m, anticorps LOC100061656, anticorps LOC100090399, anticorps a2m.S, anticorps LOC100469973, anticorps LOC100595735, anticorps PZP, anticorps LOC100353095, anticorps LOC101122940, anticorps LOC101801552, anticorps LOC100911545

Sujet: Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
Alias Symbols: CPAMD5, DKFZp779B086, FWP007, S863-7, A2MD
Protein Interaction Partner: MAPK6, CDK7, CDK11A, HIPK1, FBXO6, CFTR, TP63, TGM2, IFIT3, DNAJB1, GCDH, FARSA, ENO2, ELAVL3, CYP2C18, CYP2C8, ATP1A1, APP, APOE, ACTB, A2M, RNF32, SWSAP1, TRAPPC5, EVI5L, EGLN2, IGSF8, PRAM1, MLST8, STAMBPL1, RETN, FBXL12, ECSIT, FIS1, EXOSC1, IFIT5, NC
Protein Size: 1474

Poids moléculaire: 161 kDa

ID gène: 2

NCBI Accession: NM_000014, NP_000005

UniProt: P01023

Pathways: Lipid Metabolism