RPS27A anticorps (Middle Region)
Aperçu rapide pour RPS27A anticorps (Middle Region) (ABIN2788060)
Antigène
Voir toutes RPS27A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- LRGGAKKRKK KSYTTPKKNK HKRKKVKLAV LKYYKVDENG KISRLRRECP
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 79%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against RPS27A. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human RPS27A
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 156 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RPS27A (Ribosomal Protein S27a (RPS27A))
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Autre désignation
- RPS27A
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Sujet
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Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin, similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.
Alias Symbols: CEP80, UBA80, UBCEP1, UBCEP80, UBC, S27A
Protein Interaction Partner: CALCOCO2, DAZAP2, UBC, MDM2, TRIM25, EED, TP53, RNF11, rev, TUBA4A, PARK2, CDK2, PAN2, ZNF512B, SMAD2, ITGA4, FN1, CDK11B, UBL4A, VCAM1, RPL21, RPL19, RPL18A, RPL18, RPL17, RPL15, RPL11, RPL9, RPL7A, RPL6, RPL5, RPL4, RPL37A, RPL31, RPL24, RPL23A, RPL22,
Protein Size: 156 -
Poids moléculaire
- 18 kDa
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ID gène
- 6233
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NCBI Accession
- NM_002954, NP_002945
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UniProt
- P62979
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Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, EGFR Downregulation
Antigène
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