PEN2 anticorps (N-Term)

N° du produit ABIN2788067

Cet anticorps anti-PEN2 Polyclonal Lapin (ABIN2788067) détecte spécifiquement PEN2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour PEN2 anticorps (N-Term) (ABIN2788067)

Antigène: PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PEN2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PEN2 anticorps

Épitope: N-Term

Fonction: Psenen Antibody - N-terminal region

Séquence: LGGFAFLPFL WLVNIFWFFR EAFLAPAYTE QSQIKGYVWR SAVGFLFWVI

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against Psenen. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59440-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PEN2

Antigène: PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

Autre désignation: Psenen

Sujet:

Targeted Subunit: PEN-2

Background Information: Psenen is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.

Gene Name: Presenilin enhancer 2 homolog (C. elegans)

Alternative Symbols: Pen-2, 1700023M09Rik

Protein Name: Gamma-secretase subunit PEN-2

Poids moléculaire: 12kDa

ID gène: 66340

NCBI Accession: NP_079774

UniProt: Q9CQR7

Pathways: Signalisation Notch, Neurotrophin Signaling Pathway