PEN2 anticorps (N-Term)
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- Antigène Voir toutes PEN2 (PSENEN) Anticorps
- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien, Cheval, Cobaye, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PEN2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LGGFAFLPFL WLVNIFWFFR EAFLAPAYTE QSQIKGYVWR SAVGFLFWVI
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against Psenen. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product PSENEN Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 101 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
- Autre désignation
- Psenen (PSENEN Produits)
- Synonymes
- anticorps MSTP064, anticorps PEN-2, anticorps PEN2, anticorps Psenen, anticorps ACYPI006208, anticorps 1700023M09Rik, anticorps Pen-2, anticorps RGD1312037, anticorps CG33198, anticorps Dmel\\CG33198, anticorps anon-AE003800.1, anticorps dPen-2, anticorps psenen, anticorps pen-2, anticorps pen2, anticorps zgc:109727, anticorps presenilin enhancer gamma-secretase subunit, anticorps presenilin enhancer 2, anticorps presenilin enhancer gamma secretase subunit, anticorps Gamma-secretase subunit pen-2, anticorps presenilin enhancer, anticorps presenilin enhancer gamma secretase subunit S homeolog, anticorps PSENEN, anticorps PEN2, anticorps Psenen, anticorps pen-2, anticorps psenen.S, anticorps psenen
- Sujet
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Psenen is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
Alias Symbols: 1700023M09Rik, MGC102026
Protein Interaction Partner: Psen2, Psen1,
Protein Size: 101 - Poids moléculaire
- 12 kDa
- ID gène
- 66340
- NCBI Accession
- NM_025498, NP_079774
- UniProt
- Q9CQR7
- Pathways
- Signalisation Notch, Neurotrophin Signaling Pathway
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