Metabotropic Glutamate Receptor 3 anticorps (C-Term)

N° du produit ABIN2788133

Détail du produit anti-Metabotropic Glutamate Receptor 3 anticorps

Antigène: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 3 est non-conjugé

Application: Western Blotting (WB)

Séquence: RDFWEQKFQC SLQNKRNHRR VCDKHLAIDS SNYEQESKIM FVVNAVYAMA

Homologie: Cow: 92%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against GRM3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human GRM3

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Metabotropic Glutamate Receptor 3

Antigène: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Autre désignation: GRM3 (GRM3 Produits)

Synonymes: anticorps GLUR3, anticorps GPRC1C, anticorps MGLUR3, anticorps mGlu3, anticorps 0710001G23Rik, anticorps Gprc1c, anticorps mGluR3, anticorps glutamate metabotropic receptor 3, anticorps glutamate receptor, metabotropic 3, anticorps GRM3, anticorps Grm3

Sujet: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Alias Symbols: GLUR3, mGlu3, GPRC1C, MGLUR3
Protein Size: 537

Poids moléculaire: 59 kDa

ID gène: 2913

NCBI Accession: NM_000840, NP_000831

UniProt: Q14832

Pathways: cAMP Metabolic Process, Synaptic Membrane