CERKL anticorps (N-Term)

N° du produit ABIN2788233

Cet anticorps Lapin Polyclonal détecte spécifiquement CERKL dans WB. Il présente une réactivité avec des échantillons de Humain, Lapin, Cheval, Chien, Cobaye, Rat, Boeuf (Vache) et Porc.

Aperçu rapide pour CERKL anticorps (N-Term) (ABIN2788233)

Antigène: CERKL (Ceramide Kinase-Like (CERKL))

Reactivité: Humain, Lapin, Cheval, Chien, Cobaye, Rat, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CERKL est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CERKL anticorps

Épitope: N-Term

Fonction: CERKL Antibody - N-terminal region

Séquence: TLDLINLSED HCDIWFRQFK KILAGFPNRP KSLKILLNPQ SHKKEATQVY

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against CERKL. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CERKL

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59828-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CERKL

Antigène: CERKL (Ceramide Kinase-Like (CERKL))

Autre désignation: CERKL

Sujet:

Background Information: This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.

Gene Name: Ceramide kinase-like

Alternative Symbols: RP26

Protein Name: Ceramide kinase-like protein

Poids moléculaire: 59kDa

ID gène: 375298

NCBI Accession: NP_963842

UniProt: Q49MI3