DNAJC2 anticorps (C-Term)
Aperçu rapide pour DNAJC2 anticorps (C-Term) (ABIN2788243)
Antigène
Voir toutes DNAJC2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- EINEQIRKEK EEAEARMRQA SKNTEKSTGG GGNGSKNWSE DDLQLLIKAV
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Homologie
- Cow: 86%, Dog: 92%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against DNAJC2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human DNAJC2
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 621 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
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Autre désignation
- DNAJC2
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Sujet
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This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.
Alias Symbols: MPHOSPH11, MPP11, ZRF1, ZUO1
Protein Interaction Partner: HIST2H2AA3, UBC, RNF2, HSPA14, HSPA8,
Protein Size: 621 -
Poids moléculaire
- 72 kDa
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ID gène
- 27000
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NCBI Accession
- NM_014377, NP_055192
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UniProt
- Q99543
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Pathways
- Chromatin Binding
Antigène
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