ADRA2A anticorps (C-Term)

N° du produit ABIN2788284

L’anticorps Lapin Polyclonal anti-ADRA2A a été validé pour WB. Il convient pour détecter ADRA2A dans des échantillons de Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye et Porc.

Aperçu rapide pour ADRA2A anticorps (C-Term) (ABIN2788284)

Antigène: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRA2A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ADRA2A anticorps

Épitope: C-Term

Séquence: RRPERGPRGK GKARASQVKP GDSLPRRGPG ATGIGTPAAG PGEERVGAAK

Homologie: Cow: 92%, Dog: 85%, Guinea Pig: 79%, Human: 100%, Mouse: 79%, Pig: 85%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against ADRA2A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ADRA2A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 450 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ADRA2A

Antigène: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Autre désignation: ADRA2A

Sujet: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons, the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences.
Alias Symbols: ADRA2, ADRA2R, ADRAR, ALPHA2AAR, ZNF32
Protein Interaction Partner: GNAO1, ADRA2A, SNTA1, GNG2, GNB1, GNAI2, UCHL1, EIF2B1, YWHAZ, PRKCD, GNAI1, ADRBK1, ADRB1, PPP1R9B,
Protein Size: 450

Poids moléculaire: 49 kDa

ID gène: 150

NCBI Accession: NM_000681, NP_000672

UniProt: P08913

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity