alpha Adaptin anticorps (C-Term)

N° du produit ABIN2788287

Cet anticorps anti-alpha Adaptin est un anticorps Lapin Polyclonal détectant alpha Adaptin dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cheval, Lapin et Cobaye.

Aperçu rapide pour alpha Adaptin anticorps (C-Term) (ABIN2788287)

Antigène: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha Adaptin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-alpha Adaptin anticorps

Épitope: C-Term

Séquence: ILAKLKRKKG PGAGSALDDG RRDPSSNDIN GGMEPTPSTV STPSPSADLL

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against AP2A1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human AP2A1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 955 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur alpha Adaptin

Antigène: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Autre désignation: AP2A1

Sujet: This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined.
Alias Symbols: ADTAA, AP2-ALPHA, CLAPA1
Protein Interaction Partner: SUMO2, SUMO3, UBC, EGFR, EPHA2, ABCB11, RPA3, RPA2, RPA1, BIN1, PIN1, GRB2, PPP6R3, RNF11, ARRB1, MMS19, SMAD9, ITGA4, FN1, DAB2, VCAM1, PICALM, AP2A2, SHC1, MYO6, GRK5, EPS15, CRK, AP2M1, ABL1, AMPH, Epn1, RALBP1, REPS2, SYNJ1, SHBG, BRCA1, ARRB2, Edc4,
Protein Size: 955

Poids moléculaire: 105 kDa

ID gène: 160

NCBI Accession: NM_130787, NP_570603

UniProt: O95782

Pathways: Signalisation Notch, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation