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alpha Adaptin anticorps (C-Term)

AP2A1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Lapin, Cheval, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2788287
  • Antigène Voir toutes alpha Adaptin (AP2A1) Anticorps
    alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))
    Épitope
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 48
    • 17
    • 14
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Lapin, Cheval, Cobaye
    Hôte
    • 35
    • 8
    • 5
    Lapin
    Clonalité
    • 38
    • 10
    Polyclonal
    Conjugué
    • 25
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp alpha Adaptin est non-conjugé
    Application
    • 36
    • 23
    • 22
    • 11
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    ILAKLKRKKG PGAGSALDDG RRDPSSNDIN GGMEPTPSTV STPSPSADLL
    Homologie
    Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against AP2A1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human AP2A1
    Top Product
    Discover our top product AP2A1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 955 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))
    Autre désignation
    AP2A1 (AP2A1 Produits)
    Synonymes
    anticorps ADTAA, anticorps AP2-ALPHA, anticorps CLAPA1, anticorps adtaa, anticorps clapa1, anticorps ap2-alpha, anticorps AP2A1, anticorps Adtaa, anticorps adaptor related protein complex 2 alpha 1 subunit, anticorps adaptor-related protein complex 2, alpha 1 subunit, anticorps AP-2 complex subunit alpha-1, anticorps AP2A1, anticorps ap2a1, anticorps Ap2a1, anticorps EDI_093420, anticorps EDI_259990
    Sujet
    This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined.
    Alias Symbols: ADTAA, AP2-ALPHA, CLAPA1
    Protein Interaction Partner: SUMO2, SUMO3, UBC, EGFR, EPHA2, ABCB11, RPA3, RPA2, RPA1, BIN1, PIN1, GRB2, PPP6R3, RNF11, ARRB1, MMS19, SMAD9, ITGA4, FN1, DAB2, VCAM1, PICALM, AP2A2, SHC1, MYO6, GRK5, EPS15, CRK, AP2M1, ABL1, AMPH, Epn1, RALBP1, REPS2, SYNJ1, SHBG, BRCA1, ARRB2, Edc4,
    Protein Size: 955
    Poids moléculaire
    105 kDa
    ID gène
    160
    NCBI Accession
    NM_130787, NP_570603
    UniProt
    O95782
    Pathways
    Signalisation Notch, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation
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