F2RL2 anticorps (C-Term)
Aperçu rapide pour F2RL2 anticorps (C-Term) (ABIN2788315)
Antigène
Voir toutes F2RL2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- F2RL2 Antibody - C-terminal region
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Séquence
- HANYYYNNTD GLYFIYLIAL CLGSLNSCLD PFLYFLMSKT RNHSTAYLTK
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Homologie
- Cow: 77%, Human: 100%, Pig: 77%
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Attributs du produit
- This is a rabbit polyclonal antibody against F2RL2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human F2RL2
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60037-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- F2RL2 (Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2))
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Autre désignation
- F2RL2
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Sujet
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Background Information: Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues.
Gene Name: Coagulation factor II (thrombin) receptor-like 2
Alternative Symbols: PAR3, PAR-3
Protein Name: Proteinase-activated receptor 3
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Poids moléculaire
- 42kDa
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ID gène
- 2151
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NCBI Accession
- NP_004092
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UniProt
- O00254
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Pathways
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
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