Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This F2RL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human F2RL2.
anticorps PAR-3, anticorps PAR3, anticorps par3, anticorps Cf-2, anticorps Cf2, anticorps FII, anticorps thrombin, anticorps F730031A08, anticorps f2, anticorps f2rl2, anticorps coagulation factor II thrombin receptor like 2, anticorps coagulation factor II (thrombin) receptor-like 2, anticorps coagulation factor II, anticorps coagulation factor II, thrombin, anticorps coagulation factor II, thrombin L homeolog, anticorps coagulation factor II (thrombin) receptor-like 2 L homeolog, anticorps F2RL2, anticorps f2rl2, anticorps F2, anticorps F2rl2, anticorps f2.L, anticorps f2rl2.L
Sujet
Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues.