MAPKAP Kinase 2 anticorps (Middle Region)
Aperçu rapide pour MAPKAP Kinase 2 anticorps (Middle Region) (ABIN2788401)
Antigène
Voir toutes MAPKAP Kinase 2 (MAPKAPK2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- KLTDFGFAKE TTQNALQTPC YTPYYVAPEV LGPEKYDKSC DMWSLGVIMY
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against MAPKAPK2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human MAPKAPK2
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 370 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))
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Autre désignation
- MAPKAPK2
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Sujet
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MAPKAPK2 is a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo.
Alias Symbols: 3PK, MAPKAP3, MK2, MK-2, MAPKAP-K2
Protein Interaction Partner: PIAS2, DDX5, MAPK14, AKT1, HSPB1, MAPKAPK2, UBC, Ube2j1, TCF3, DES, MAP2K6, MAPK11, MAPK3, PABPC1, HNRNPA0, PARN, LIMK1, HSF1, CHEK1, CDC25B, ALOX5, ZFP36L1, ESR1, COPS5, CUL3, MAPKAPK5, MAPK1, ELAVL1, PHC2, CSNK2B, ARPC5, EEF2K, BAG2, YWHAZ, SRF, SHC1, E
Protein Size: 370 -
Poids moléculaire
- 42 kDa
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ID gène
- 9261
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NCBI Accession
- NM_004635, NP_004626
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UniProt
- Q16644
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Pathways
- Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
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