MAPKAP Kinase 3 anticorps (C-Term)

N° du produit ABIN2788402

Cet anticorps anti-MAPKAP Kinase 3 Polyclonal Lapin (ABIN2788402) détecte spécifiquement MAPKAP Kinase 3 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Porc, Lapin, Cobaye, Cheval, Boeuf (Vache) et Chien.

Aperçu rapide pour MAPKAP Kinase 3 anticorps (C-Term) (ABIN2788402)

Antigène: MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))

Reactivité: Humain, Souris, Rat, Porc, Lapin, Cobaye, Cheval, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPKAP Kinase 3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAPKAP Kinase 3 anticorps

Épitope: C-Term

Séquence: KEEMTSALAT MRVDYDQVKI KDLKTSNNRL LNKRRKKQAG SSSASQGCNN

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MAPKAPK3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human MAPKAPK3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 382 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAPKAP Kinase 3

Antigène: MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))

Autre désignation: MAPKAPK3

Sujet: MAPKAPK3 is a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.
Alias Symbols: 3PK, MAPKAP3, MK-3, MAPKAP-K3, MAPKAPK-3
Protein Interaction Partner: UBC, TCF3, MAPK11, MAPK14, HSPB1, APP, LNX1, RNF2, PHC2, BMI1, Nedd4, NEDD4L, COPS6, SUMO3, SMS, RAB2A, IGHM, EZH2, MAPK13, EEF2K, EEF2, CBX4,
Protein Size: 382

Poids moléculaire: 43 kDa

ID gène: 7867

NCBI Accession: NM_004635, NP_004626

UniProt: Q16644

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades