VEGFA anticorps (C-Term)

N° du produit ABIN2788641

Cet anticorps Lapin Polyclonal détecte spécifiquement VEGFA dans WB et IHC. Il présente une réactivité envers Humain, Rat, Souris, Chien, Lapin, Boeuf (Vache), Cheval, Mouton et Cobaye.

Aperçu rapide pour VEGFA anticorps (C-Term) (ABIN2788641)

Antigène: VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

Reactivité: Humain, Rat, Souris, Chien, Lapin, Boeuf (Vache), Cheval, Mouton, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VEGFA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-VEGFA anticorps

Épitope: C-Term

Séquence: SFLQHNKCEC RPKKDRARQE KKSVRGKGKG QKRKRKKSRY KSWSVCDKPR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against VEGFA. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 351 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur VEGFA

Antigène: VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

Autre désignation: VEGFA

Sujet: This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome.
Alias Symbols: MGC70609, MVCD1, VEGF, VPF
Protein Interaction Partner: ILF3, HNRNPL, NRP1, FLT1, LYVE1, KDR, PRRG4, VPS35, U2AF1, Flt4, ELAVL1, CRYAB, HNRNPD, HGS, UBC, HSP90AA1, HSPA4, YBX3, ADAMTS1, IGFBP7, NRP2, VEGFB, SEMA3F, PGF, EPHB2, TNXB, GPC1, VTN, VEGFA, SPARC, AKT1, YBX1, CTGF, RB1, HIF1A,
Protein Size: 351

Poids moléculaire: 40 kDa

ID gène: 7422

NCBI Accession: NM_001204385, NP_001191314

UniProt: P15692

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling