CD44 anticorps (C-Term)

N° du produit ABIN2788656

Cet anticorps Lapin Polyclonal détecte spécifiquement CD44 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval et Cobaye.

Aperçu rapide pour CD44 anticorps (C-Term) (ABIN2788656)

Antigène: CD44

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD44 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD44 anticorps

Épitope: C-Term

Séquence: SGNGAVEDRK PSGLNGEASK SQEMVHLVNK ESSETPDQFM TADETRNLQN

Homologie: Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CD44. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CD44

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 361 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD44

Antigène: CD44

Autre désignation: CD44

Sujet: The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined.
Alias Symbols: CDW44, CSPG8, ECMR-III, HCELL, IN, LHR, MC56, MDU2, MDU3, MGC10468, MIC4, MUTCH-I, Pgp1, HUTCH-I
Protein Interaction Partner: UBC, NF2, NEDD8, BAG1, DPP8, VHL, SRC, ANK1, ATF2, FMNL1, IQGAP1, SLC3A2, STAT3, ITGB1, FLOT2, EP300, CAV1, PRKCZ, ELAVL1, ARHGEF12, ARHGEF1, PKN1, DMP1, HMMR, TIAM1, ERBB4, VAV2, GARS, TGFBR2, TGFBR1, CD4, MMP7, SRGN, SPP1, LCK, IGFBP3, CD74, FYN, FGF2,
Protein Size: 361

Poids moléculaire: 40 kDa

ID gène: 960

NCBI Accession: NM_001001391, NP_001001391

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling