Clusterin anticorps (C-Term)

N° du produit ABIN2788692

Cet anticorps Lapin Polyclonal détecte spécifiquement Clusterin dans WB et IHC. Il présente une réactivité envers Humain, Rat, Souris, Lapin, Cheval et Cobaye.

Aperçu rapide pour Clusterin anticorps (C-Term) (ABIN2788692)

Antigène: Clusterin (CLU)

Reactivité: Humain, Rat, Souris, Lapin, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Clusterin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Clusterin anticorps

Épitope: C-Term

Séquence: CREILSVDCS TNNPSQAKLR RELDESLQVA ERLTRKYNEL LKSYQWKMLN

Homologie: Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 91%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against CLU. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CLU

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 501 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Clusterin

Antigène: Clusterin (CLU)

Autre désignation: CLU

Sujet: The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.
Alias Symbols: AAG4, APOJ, CLI, KUB1, MGC24903, SGP-2, SGP2, SP-40, APO-J, NA1/NA2
Protein Interaction Partner: HYOU1, HSP90B1, HSPA5, BAX, TUFM, NUCB2, HSPA1L, TUBB6, MDM2, FOS, CDK19, APOA1, KEAP1, POLR1C, RPL23, KLF11, BAG6, RBBP8, MAPK9, PDIA3, CYP2E1, BCL2L1, TSC22D4, MDC1, LIG4, PAXIP1, CLUAP1, IL24, PRNP, PON1, HSPD1, APP, FBXO6, LYZ, LRP2, HBA1, XRCC6, ELN,
Protein Size: 501

Poids moléculaire: 58 kDa

ID gène: 1191

NCBI Accession: NM_001831, NP_001822

UniProt: P10909

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling