VASP anticorps (C-Term)

N° du produit ABIN2788720

Cet anticorps anti-VASP est un anticorps Lapin Polyclonal détectant VASP dans WB. Adapté pour Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval et Cobaye.

Aperçu rapide pour VASP anticorps (C-Term) (ABIN2788720)

Antigène: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VASP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-VASP anticorps

Épitope: C-Term

Séquence: SGRSGGGGLM EEMNAMLARR RKATQVGEKT PKDESANQEE PEARVPAQSE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against VASP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human VASP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 380 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur VASP

Antigène: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Autre désignation: VASP

Sujet: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
Alias Symbols: -
Protein Interaction Partner: ABI3, FGFR1OP, ABI2, SCGB2A2, CEP250, TP53, XIRP1, UBC, FAT1, FOXK1, PPP4R2, PAAF1, PRPF40A, RPP38, PRMT5, POP7, CUL4B, PSMA5, DDB1, APBB1, YWHAQ, NR4A1, YWHAE, DMRTB1, NPM1, VCAM1, SAT1, ITGA4, FN1, AMOT, SF3B2, SF3A3, ATP6V1F, CPNE3, SRSF9, UBE2N, UAP1,
Protein Size: 380

Poids moléculaire: 42 kDa

ID gène: 7408

NCBI Accession: NM_003370, NP_003361

UniProt: P50552

Pathways: TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation