OGG1 anticorps (C-Term)

N° du produit ABIN2788728

Cet anticorps anti-OGG1 Polyclonal Lapin (ABIN2788728) détecte spécifiquement OGG1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache) et Porc.

Aperçu rapide pour OGG1 anticorps (C-Term) (ABIN2788728)

Antigène: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OGG1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-OGG1 anticorps

Épitope: C-Term

Fonction: OGG1 Antibody - C-terminal region

Séquence: AVPVDVHMWH IAQRDYSWHP TTSQAKGPSP QTNKELGNFF RSLWGPYAGW

Specificité: Directed against isoforms 2D, 1A, 1B, 2E.

Homologie: Cow: 93%, Dog: 100%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 92%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against OGG1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61228-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur OGG1

Antigène: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Autre désignation: OGG1

Sujet:

Background Information: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization.

Gene Name: 8-oxoguanine DNA glycosylase

Alternative Symbols: HMMH, MUTM, OGH1, HOGG1

Protein Name: N-glycosylase/DNA lyase

Poids moléculaire: 38kDa

ID gène: 4968

NCBI Accession: NP_058438

UniProt: O15527

Pathways: Réparation de l'ADN