HCK anticorps (C-Term)

N° du produit ABIN2788734

Cet anticorps Lapin Polyclonal détecte spécifiquement HCK dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour HCK anticorps (C-Term) (ABIN2788734)

Antigène: HCK (Hemopoietic Cell Kinase (HCK))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HCK est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HCK anticorps

Épitope: C-Term

Séquence: LVKLHAVVTK EPIYIITEFM AKGSLLDFLK SDEGSKQPLP KLIDFSAQIA

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against HCK. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human HCK

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 504 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HCK

Antigène: HCK (Hemopoietic Cell Kinase (HCK))

Autre désignation: HCK

Sujet: The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
Alias Symbols: JTK9, p59Hck, p61Hck
Protein Interaction Partner: NOTCH2NL, KRTAP10-9, KRT40, GOPC, MTUS2, SPRR2A, STAT3, ACTB, Mbp, MED28, RUFY1, WNT2, HSP90AA1, ERBB3, ABL2, CBL, APP, PAK2, nef, TNK2, ADAM15, CREBBP, FASLG, SH3KBP1, KHDRBS1, MYC, UBC, SRC, MAP4K5, CHST15, ELMO1, SF3B3, EVL, IRF2BPL, SH3BP1, INPP5D, AG
Protein Size: 504

Poids moléculaire: 55 kDa

ID gène: 3055

NCBI Accession: NM_001172131, NP_001165602

UniProt: P08631

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling