HCK anticorps (C-Term)
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- Antigène Voir toutes HCK Anticorps
- HCK (Hemopoietic Cell Kinase (HCK))
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Épitope
- C-Term
- Reactivité
- Humain, Souris, Rat, Cobaye, Cheval, Lapin, Boeuf (Vache), Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HCK est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LVKLHAVVTK EPIYIITEFM AKGSLLDFLK SDEGSKQPLP KLIDFSAQIA
- Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against HCK. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human HCK
- Top Product
- Discover our top product HCK Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 504 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- HCK (Hemopoietic Cell Kinase (HCK))
- Autre désignation
- HCK (HCK Produits)
- Synonymes
- anticorps laloo, anticorps HCK, anticorps MGC107870, anticorps JTK9, anticorps p59Hck, anticorps p61Hck, anticorps AI849071, anticorps Bmk, anticorps Hctk, anticorps p56Hck, anticorps HCK proto-oncogene, Src family tyrosine kinase L homeolog, anticorps HCK proto-oncogene, Src family tyrosine kinase, anticorps hemopoietic cell kinase, anticorps hck.L, anticorps HCK, anticorps hck, anticorps Hck
- Sujet
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The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
Alias Symbols: JTK9, p59Hck, p61Hck
Protein Interaction Partner: NOTCH2NL, KRTAP10-9, KRT40, GOPC, MTUS2, SPRR2A, STAT3, ACTB, Mbp, MED28, RUFY1, WNT2, HSP90AA1, ERBB3, ABL2, CBL, APP, PAK2, nef, TNK2, ADAM15, CREBBP, FASLG, SH3KBP1, KHDRBS1, MYC, UBC, SRC, MAP4K5, CHST15, ELMO1, SF3B3, EVL, IRF2BPL, SH3BP1, INPP5D, AG
Protein Size: 504 - Poids moléculaire
- 55 kDa
- ID gène
- 3055
- NCBI Accession
- NM_001172131, NP_001165602
- UniProt
- P08631
- Pathways
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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