CAMK2B anticorps (C-Term)
Aperçu rapide pour CAMK2B anticorps (C-Term) (ABIN2788742)
Antigène
Voir toutes CAMK2B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- NPHVHVIGED AACIAYIRLT QYIDGQGRPR TSQSEETRVW HRRDGKWQNV
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against CAMK2B. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human CAMK2B
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 542 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))
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Autre désignation
- CAMK2B
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Sujet
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The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene.
Alias Symbols: CAM2, CAMK2, CAMKB, MGC29528
Protein Interaction Partner: KRTAP10-11, KRTAP19-7, KRTAP19-5, FAM171A2, MGAT5B, CCM2L, TTC5, AP5B1, MRPL11, SEMA4G, SPRYD7, MED18, POP5, RBFOX2, ACOT7, RBPMS, MORF4L1, MAD2L2, RPL11, RAP2B, PHKB, CAMK2B, MVP, SMYD3, UBC, ATXN1, HSP90AA1, Rad23a, THRB, RXRG, YWHAB, CAMK2N2, CAMK2D, A
Protein Size: 542 -
Poids moléculaire
- 60 kDa
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ID gène
- 816
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NCBI Accession
- NM_172078, NP_742075
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UniProt
- Q53H78
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Pathways
- Signalisation WNT, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
Antigène
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