TNFAIP3 anticorps (C-Term)

N° du produit ABIN2788768

Cet anticorps Lapin Polyclonal détecte spécifiquement TNFAIP3 dans WB. Il présente une réactivité envers Humain, Rat et Chien.

Aperçu rapide pour TNFAIP3 anticorps (C-Term) (ABIN2788768)

Antigène: TNFAIP3 (Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))

Reactivité: Humain, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFAIP3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TNFAIP3 anticorps

Épitope: C-Term

Séquence: QENSEQGRRE GHAQNPMEPS VPQLSLMDVK CETPNCPFFM SVNTQPLCHE

Homologie: Dog: 79%, Human: 100%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against TNFAIP3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human TNFAIP3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TNFAIP3

Antigène: TNFAIP3 (Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))

Autre désignation: TNFAIP3

Sujet: This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.
Alias Symbols: A20, AISBL, OTUD7C, TNFA1P2
Protein Size: 471

Poids moléculaire: 51 kDa

ID gène: 7128

NCBI Accession: NM_001270507, NP_001257436

UniProt: P21580

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Production of Molecular Mediator of Immune Response