HRH3 anticorps (N-Term)

N° du produit ABIN2789052

L’anticorps anti-HRH3 Polyclonal Lapin est utilisé pour la détection de HRH3 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Cobaye, Chien et Lapin. Il a été validé pour WB.

Aperçu rapide pour HRH3 anticorps (N-Term) (ABIN2789052)

Antigène: HRH3 (Histamine Receptor H3 (HRH3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Cobaye, Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HRH3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HRH3 anticorps

Épitope: N-Term

Fonction: Hrh3 Antibody - N-terminal region

Séquence: VFNIVLISYD RFLSVTRAVS YRAQQGDTRR AVRKMALVWV LAFLLYGPAI

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Hrh3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Hrh3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62180-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur HRH3

Antigène: HRH3 (Histamine Receptor H3 (HRH3))

Autre désignation: Hrh3

Sujet:

Background Information: This gene encodes a histamine H3 receptor that belongs to the superfamily of G-protein coupled receptors. This protein functions as a presynaptic autoreceptor on histamine neurons in the brain, and a presynaptic heteroreceptor in nonhistamine-containing neurons in both the central and peripheral nervous systems. It is deemed a great target for the development of therapeutics for numerous disorders, including obesity, epilepsy, and such cognitive diseases as attention deficit hyperactivity disorder and Alzheimer's disease. Several alternatively spliced transcript variants encoding different isoforms, with different brain expression patterns and signaling properties, have been described for this gene.

Gene Name: histamine receptor H3

Alternative Symbols: -

Protein Name: Histamine H3 receptor

Poids moléculaire: 48kDa

ID gène: 85268

NCBI Accession: NP_445958

UniProt: Q9QYN8

Pathways: cAMP Metabolic Process, Feeding Behaviour