CD86 anticorps (C-Term)

N° du produit ABIN2789334

Cet anticorps Lapin Polyclonal détecte spécifiquement CD86 dans WB. Il présente une réactivité envers Humain et Porc.

Aperçu rapide pour CD86 anticorps (C-Term) (ABIN2789334)

Antigène: CD86

Reactivité: Humain, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD86 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD86 anticorps

Épitope: C-Term

Séquence: WKKKKRPRNS YKCGTNTMER EESEQTKKRE KIHIPERSDE AQRVFKSSKT

Homologie: Human: 100%, Pig: 92%

Attributs du produit: This is a rabbit polyclonal antibody against CD86. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 217 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD86

Antigène: CD86

Autre désignation: CD86

Sujet: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Alias Symbols: B7-2, B70, CD28LG2, LAB72, MGC34413, B7.2
Protein Interaction Partner: UBC, CTLA4, ECE2, PARP1, MARCH1, MARCH8, CD86, CD28, CD80,
Protein Size: 217

Poids moléculaire: 23 kDa

ID gène: 942

NCBI Accession: NM_175862, NP_787058

UniProt: E9PC27

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation