CD86 anticorps (C-Term)

N° du produit ABIN2789334

Cet anticorps Lapin Polyclonal détecte spécifiquement CD86 dans WB. Il présente une réactivité avec des échantillons de Humain et Porc.

Aperçu rapide pour CD86 anticorps (C-Term) (ABIN2789334)

Antigène: CD86

Reactivité: Humain, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD86 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD86 anticorps

Épitope: C-Term

Fonction: CD86 Antibody - C-terminal region

Séquence: WKKKKRPRNS YKCGTNTMER EESEQTKKRE KIHIPERSDE AQRVFKSSKT

Homologie: Human: 100%, Pig: 92%

Attributs du produit: This is a rabbit polyclonal antibody against CD86. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63007-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD86

Antigène: CD86

Autre désignation: CD86

Sujet:

Background Information: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

Gene Name: CD86 Molecule

Alternative Symbols: B70, B7-2, B7.2, LAB72, CD28LG2

Protein Name: T-lymphocyte activation antigen CD86 Ensembl ENSP00000420230

Poids moléculaire: 23kDa

ID gène: 942

NCBI Accession: NP_787058

UniProt: E9PC27

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation