Poliovirus Receptor anticorps (N-Term)
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- Antigène Voir toutes Poliovirus Receptor (PVR) Anticorps
- Poliovirus Receptor (PVR)
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Poliovirus Receptor est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- FHQTQGPSYS ESKRLEFVAA RLGAELRNAS LRMFGLRVED EGNYTCLFVT
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PVR. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product PVR Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 417 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Poliovirus Receptor (PVR)
- Autre désignation
- PVR (PVR Produits)
- Sujet
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The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD155, FLJ25946, HVED, NECL5, Necl-5, PVS, TAGE4
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, SLC30A2, TIGIT, TNFRSF12A, WNK1, PLA2G3, UBC, ZC3HAV1, ELAVL1, CD226, PVRL3, PVRL1, CD96, AP1M2, DYNLT3, VTN, PVR, DYNLT1,
Protein Size: 417 - Poids moléculaire
- 45 kDa
- ID gène
- 5817
- NCBI Accession
- NM_006505, NP_006496
- UniProt
- P15151
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
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