BMP4 anticorps (C-Term)

N° du produit ABIN2789354

Cité dans 1 publication. Cet anticorps anti-BMP4 Polyclonal Lapin (ABIN2789354) détecte spécifiquement BMP4 dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Lapin, Porc, Boeuf (Vache), Chien, Chévre, Mouton, Cobaye et Cheval.

Aperçu rapide pour BMP4 anticorps (C-Term) (ABIN2789354)

Antigène: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reactivité: Humain, Rat, Souris, Lapin, Porc, Boeuf (Vache), Chien, Chévre, Mouton, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMP4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BMP4 anticorps

Épitope: C-Term

Fonction: BMP4 Antibody - C-terminal region

Séquence: NWAQLRPLLV TFGHDGRGHA LTRRRRAKRS PKHHSQRARK KNKNCRRHSL

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against BMP4. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63062-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-BMP4 (ABIN2789354)

Ganti, Hunt, Parapuram, Hunt: "Vitreous modulation of gene expression in low-passage human retinal pigment epithelial cells." dans: Investigative ophthalmology & visual science, Vol. 48, Issue 4, pp. 1853-63, (2007) (PubMed).

Détails sur BMP4

Antigène: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Autre désignation: BMP4

Sujet:

Background Information: The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Gene Name: Bone morphogenetic protein 4

Alternative Symbols: ZYME, BMP2B, OFC11, BMP2B1, MCOPS6

Protein Name: Bone morphogenetic protein 4

Poids moléculaire: 40 kDa

ID gène: 652

NCBI Accession: NP_001193

UniProt: P12644

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development