CD33 anticorps (N-Term)

N° du produit ABIN2789356

L’anticorps anti-CD33 Polyclonal Lapin est utilisé pour la détection de CD33 dans des échantillons de Humain, Boeuf (Vache) et Cheval. Il a été validé pour WB.

Aperçu rapide pour CD33 anticorps (N-Term) (ABIN2789356)

Antigène: CD33

Reactivité: Humain, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD33 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD33 anticorps

Épitope: N-Term

Fonction: CD33 Antibody - N-terminal region

Séquence: HPIPYYDKNS PVHGYWFREG AIISRDSPVA TNKLDQEVQE ETQGRFRLLG

Homologie: Cow: 79%, Horse: 79%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CD33. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63067-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD33

Antigène: CD33

Autre désignation: CD33

Sujet:

Background Information: CD33 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 induces apoptosis in acute myeloid leukemia (in vitro).

Gene Name: CD33 Molecule

Alternative Symbols: p67, SIGLEC3, SIGLEC-3

Protein Name: Myeloid cell surface antigen CD33

Poids moléculaire: 38kDa

ID gène: 945

NCBI Accession: NP_001763

UniProt: P20138