Angiopoietin 1 anticorps (N-Term)

N° du produit ABIN2789374

L’anticorps Lapin Polyclonal anti-Angiopoietin 1 a été validé pour WB. Il convient pour détecter Angiopoietin 1 dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Porc, Lapin et Cheval.

Aperçu rapide pour Angiopoietin 1 anticorps (N-Term) (ABIN2789374)

Antigène: Angiopoietin 1 (ANGPT1)

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Porc, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiopoietin 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Angiopoietin 1 anticorps

Épitope: N-Term

Séquence: FAFLAAILTH IGCSNQRRSP ENSGRRYNRI QHGQCAYTFI LPEHDGNCRE

Homologie: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ANGPT1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 498 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Angiopoietin 1

Antigène: Angiopoietin 1 (ANGPT1)

Autre désignation: ANGPT1

Sujet: Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: AGP1, AGPT, ANG1
Protein Interaction Partner: UBC, ANGPT2, ANGPT1, TEK, ITGA5,
Protein Size: 498

Poids moléculaire: 55 kDa

ID gène: 284

NCBI Accession: NM_001146, NP_001137

UniProt: Q15389

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process