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Angiopoietin 2 anticorps (Middle Region)

ANGPT2 Reactivité: Humain, Souris, Rat, Porc, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Mouton WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2789397
  • Antigène Voir toutes Angiopoietin 2 (ANGPT2) Anticorps
    Angiopoietin 2 (ANGPT2)
    Épitope
    • 15
    • 10
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    Humain, Souris, Rat, Porc, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Mouton
    Hôte
    • 77
    • 10
    • 4
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 68
    • 26
    Polyclonal
    Conjugué
    • 48
    • 10
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Angiopoietin 2 est non-conjugé
    Application
    • 64
    • 32
    • 32
    • 13
    • 13
    • 12
    • 10
    • 10
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB)
    Séquence
    NQTTRLELQL LQHSISTNKL EKQILDQTSE INKLQNKNSF LEQKVLDMEG
    Homologie
    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against Angpt2. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of Mouse Angpt2
    Top Product
    Discover our top product ANGPT2 Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeat freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    Angiopoietin 2 (ANGPT2)
    Autre désignation
    Angpt2 (ANGPT2 Produits)
    Synonymes
    anticorps AGPT2, anticorps ANG2, anticorps Agpt2, anticorps Ang-2, anticorps Ang2, anticorps ang2, anticorps angpt2, anticorps ANGIOPOIETIN-2, anticorps ANG-2, anticorps ANGPT2, anticorps Angrp, anticorps Rnase5b, anticorps ANG3, anticorps C11orf2, anticorps C11orf3, anticorps FFR, anticorps angiopoietin 2, anticorps angiopoietin 2b, anticorps angiogenin, ribonuclease A family, member 2, anticorps VPS51, GARP complex subunit, anticorps ANGPT2, anticorps Angpt2, anticorps angpt2b, anticorps Ang2, anticorps VPS51
    Sujet
    Angpt2 binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. It can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
    Alias Symbols: Agpt2, Ang-2, Ang2
    Protein Size: 496
    Poids moléculaire
    56 kDa
    ID gène
    11601
    NCBI Accession
    NM_007426, NP_031452
    UniProt
    O35608
    Pathways
    Signalisation RTK
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