NLRP3 anticorps (N-Term)
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- Antigène Voir toutes NLRP3 Anticorps
- NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
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Épitope
- N-Term
- Reactivité
- Humain, Chien, Boeuf (Vache), Lapin, Porc, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NLRP3 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LGESVSLNKR YTRLRLIKEH RSQQEREQEL LAIGKTKTCE SPVSPIKMEL
- Homologie
- Cow: 93%, Dog: 79%, Horse: 93%, Human: 100%, Pig: 93%, Rabbit: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against NLRP3. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product NLRP3 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1036 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
- Autre désignation
- NLRP3 (NLRP3 Produits)
- Synonymes
- anticorps CIAS1, anticorps Nalp3, anticorps avp, anticorps cias1, anticorps nalp3, anticorps pypaf1, anticorps agtavprl, anticorps AGTAVPRL, anticorps AII, anticorps AVP, anticorps C1orf7, anticorps CLR1.1, anticorps FCAS, anticorps FCU, anticorps MWS, anticorps NALP3, anticorps PYPAF1, anticorps AII/AVP, anticorps Cias1, anticorps Mmig1, anticorps Pypaf1, anticorps NLR family pyrin domain containing-like, anticorps NLR family pyrin domain containing 3, anticorps NLR family, pyrin domain containing 3 L homeolog, anticorps NLR family, pyrin domain containing 3, anticorps NLRPL, anticorps NLRP3, anticorps nlrp3.L, anticorps Nlrp3
- Sujet
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This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID).
Alias Symbols: AGTAVPRL, AII, AII/AVP, AVP, C1orf7, CIAS1, CLR1.1, FCAS, FCU, FLJ95925, MWS, NALP3, PYPAF1
Protein Interaction Partner: DHX33, FAF1, SUGT1, HSP90AA1, CARD8, PYCARD, NLRC4,
Protein Size: 1036 - Poids moléculaire
- 114 kDa
- ID gène
- 114548
- NCBI Accession
- NM_004895, NP_004886
- UniProt
- Q96P20
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
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