ARHGEF1 anticorps (N-Term)

N° du produit ABIN2789444

Détail du produit anti-ARHGEF1 anticorps

Antigène: ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF1 est non-conjugé

Application: Western Blotting (WB)

Séquence: SAAVVNAIGL YMRHLGVRTK SGDKKSGRNF FRKKVMGNRR SDEPAKTKKG

Homologie: Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ARHGEF1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ARHGEF1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 912 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ARHGEF1

Antigène: ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))

Autre désignation: ARHGEF1 (ARHGEF1 Produits)

Synonymes: anticorps arhgef1, anticorps cb473, anticorps zgc:158261, anticorps ARHGEF1, anticorps GEF1, anticorps LBCL2, anticorps LSC, anticorps P115-RHOGEF, anticorps SUB1.5, anticorps Lbcl2, anticorps Lsc, anticorps Rho guanine nucleotide exchange factor (GEF) 1a, anticorps Rho guanine nucleotide exchange factor 1, anticorps Rho guanine nucleotide exchange factor (GEF) 1, anticorps arhgef1a, anticorps ARHGEF1, anticorps arhgef1, anticorps Arhgef1

Sujet: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Alias Symbols: GEF1, LBCL2, LSC, P115-RHOGEF, SUB1.5
Protein Interaction Partner: TCF4, UBC, CYFIP1, CAP2, FN1, DCUN1D1, SH3KBP1, CSNK1E, SREBF2, MEPCE, TAF10, CNKSR1, GNA13, ARHGEF1, PRKCA, CD44, RAP1A, HRAS, PIK3CA, RHOA, GNA12, ATR,
Protein Size: 912

Poids moléculaire: 102 kDa

ID gène: 9138

NCBI Accession: NM_199002, NP_945353

UniProt: Q92888

Pathways: Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling