GDF5 anticorps (C-Term)
Aperçu rapide pour GDF5 anticorps (C-Term) (ABIN2789451)
Antigène
Voir toutes GDF5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- YLFSQRRKRR APLATRQGKR PSKNLKARCS RKALHVNFKD MGWDDWIIAP
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against GDF5. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of GDF5
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 501 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GDF5 (Growth Differentiation Factor 5 (GDF5))
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Autre désignation
- GDF5
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Sujet
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The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type, brachydactyly, type C, and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.
Alias Symbols: BMP14, CDMP1, LAP4, OS5, SYNS2
Protein Interaction Partner: CHRDL2, BMPR1B, ACVR2B, HTRA1, BMPR1A, BMPR2, ACVR2A, ACVR1,
Protein Size: 501 -
Poids moléculaire
- 55 kDa
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ID gène
- 8200
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NCBI Accession
- NM_000557, NP_000548
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UniProt
- P43026
Antigène
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