GDF5 anticorps (C-Term)

N° du produit ABIN2789451

Détail du produit anti-GDF5 anticorps

Antigène: GDF5 (Growth Differentiation Factor 5 (GDF5))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GDF5 est non-conjugé

Application: Western Blotting (WB)

Séquence: YLFSQRRKRR APLATRQGKR PSKNLKARCS RKALHVNFKD MGWDDWIIAP

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GDF5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of GDF5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 501 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GDF5

Antigène: GDF5 (Growth Differentiation Factor 5 (GDF5))

Autre désignation: GDF5 (GDF5 Produits)

Synonymes: anticorps CDMP1, anticorps gdf, anticorps gdf-5, anticorps GDF5, anticorps BDA1C, anticorps BMP14, anticorps LAP4, anticorps OS5, anticorps SYM1B, anticorps SYNS2, anticorps Cdmp-1, anticorps bp, anticorps brp, anticorps Cdmp1, anticorps growth differentiation factor 5 L homeolog, anticorps growth differentiation factor 5, anticorps gdf5.L, anticorps GDF5, anticorps Gdf5

Sujet: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type, brachydactyly, type C, and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.
Alias Symbols: BMP14, CDMP1, LAP4, OS5, SYNS2
Protein Interaction Partner: CHRDL2, BMPR1B, ACVR2B, HTRA1, BMPR1A, BMPR2, ACVR2A, ACVR1,
Protein Size: 501

Poids moléculaire: 55 kDa

ID gène: 8200

NCBI Accession: NM_000557, NP_000548

UniProt: P43026