PD-L1 anticorps (C-Term)

N° du produit ABIN2789465

Cet anticorps Lapin Polyclonal détecte spécifiquement PD-L1 dans WB. Il présente une réactivité envers Humain et Cheval.

Aperçu rapide pour PD-L1 anticorps (C-Term) (ABIN2789465)

Antigène: PD-L1 (CD274 (PD-L1))

Reactivité: Humain, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PD-L1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PD-L1 anticorps

Épitope: C-Term

Séquence: HLVILGAILL CLGVALTFIF RLRKGRMMDV KKCGIQDTNS KKQSDTHLEE

Homologie: Horse: 82%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CD274. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of CD274

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 290 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PD-L1

Antigène: PD-L1 (CD274 (PD-L1))

Autre désignation: CD274

Sujet: CD274 is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Alias Symbols: B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1, PDCD1LG1, PDL1
Protein Interaction Partner: PDCD1, CD80, PTPN11,
Protein Size: 290

Poids moléculaire: 32 kDa

ID gène: 29126

NCBI Accession: NM_014143, NP_054862

UniProt: Q9NZQ7

Pathways: Cancer Immune Checkpoints