IL13 Receptor alpha 1 anticorps (N-Term)

N° du produit ABIN2789491

L’anticorps Lapin Polyclonal anti-IL13 Receptor alpha 1 a été validé pour WB. Il convient pour détecter IL13 Receptor alpha 1 dans des échantillons de Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Porc et Mouton.

Aperçu rapide pour IL13 Receptor alpha 1 anticorps (N-Term) (ABIN2789491)

Antigène: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Porc, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL13 Receptor alpha 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IL13 Receptor alpha 1 anticorps

Épitope: N-Term

Séquence: VSVENLCTVI WTWNPPEGAS SNCSLWYFSH FGDKQDKKIA PETRRSIEVP

Homologie: Cow: 92%, Dog: 85%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 85%, Rabbit: 100%, Rat: 86%, Sheep: 92%

Attributs du produit: This is a rabbit polyclonal antibody against IL13RA1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of IL13RA1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 427 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IL13 Receptor alpha 1

Antigène: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Autre désignation: IL13RA1

Sujet: The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
Alias Symbols: CD213A1, IL-13Ra, NR4
Protein Interaction Partner: UBC, IL2RG, TMEM39B, ELAVL1, TRAF3IP1, DLG4, TYK2, IL4R, IL13,
Protein Size: 427

Poids moléculaire: 47 kDa

ID gène: 3597

NCBI Accession: NM_001560, NP_001551

UniProt: P78552

Pathways: Signalistation JAK/STAT, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response