SOCS2 anticorps (C-Term)

N° du produit ABIN2789498

L’anticorps anti-SOCS2 Polyclonal Lapin est utilisé pour la détection de SOCS2 dans des échantillons de Humain, Rat, Souris, Boeuf (Vache), Porc, Chien, Lapin et Cobaye. Il a été validé pour WB.

Aperçu rapide pour SOCS2 anticorps (C-Term) (ABIN2789498)

Antigène: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Porc, Chien, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SOCS2 anticorps

Épitope: C-Term

Fonction: SOCS2 Antibody - C-terminal region

Séquence: KQFDSVVHLI DYYVQMCKDK RTGPEAPRNG TVHLYLTKPL YTSAPSLQHL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SOCS2. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63434-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur SOCS2

Antigène: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Autre désignation: SOCS2

Sujet:

Background Information: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control.

Gene Name: Suppressor of cytokine signaling 2

Alternative Symbols: CIS2, SSI2, Cish2, SSI-2, SOCS-2, STATI2

Protein Name: Suppressor of cytokine signaling 2

Poids moléculaire: 22kDa

ID gène: 8835

NCBI Accession: NP_003868

UniProt: O14508

Pathways: Signalistation JAK/STAT, Response to Growth Hormone Stimulus