MCAM anticorps (C-Term)

N° du produit ABIN2789517

Cet anticorps Lapin Polyclonal détecte spécifiquement MCAM dans WB. Il présente une réactivité envers Humain, Souris, Rat, Lapin, Chien, Porc, Cheval et Cobaye.

Aperçu rapide pour MCAM anticorps (C-Term) (ABIN2789517)

Antigène: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Reactivité: Humain, Souris, Rat, Lapin, Chien, Porc, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCAM est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MCAM anticorps

Épitope: C-Term

Séquence: STSTASPHTR ANSTSTERKL PEPESRGVVI VAVIVCILVL AVLGAVLYFL

Homologie: Dog: 79%, Guinea Pig: 77%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 79%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MCAM. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MCAM

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MCAM

Antigène: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Autre désignation: MCAM

Sujet: MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. MCAM could be an adhesion molecule active in neural crest cells during embryonic development. MCAM acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.
Protein Interaction Partner: ADRB2, UBC, HSP90AA5P, HSPA1L, ATF7IP, PTK2B, FYN,
Protein Size: 527

Poids moléculaire: 57 kDa

ID gène: 4162