ROS1 anticorps (C-Term)

N° du produit ABIN2789629

L’anticorps anti-ROS1 Polyclonal Lapin est utilisé pour la détection de ROS1 dans des échantillons de Humain, Lapin, Chien et Cheval. Il a été validé pour WB.

Aperçu rapide pour ROS1 anticorps (C-Term) (ABIN2789629)

Antigène: ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))

Reactivité: Humain, Lapin, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ROS1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ROS1 anticorps

Épitope: C-Term

Fonction: ROS1 Antibody - C-terminal region

Séquence: EGLNYMVLAT ECGQGEEKSE GPLGSQESES CGLRKEEKEP HADKDFCQEK

Homologie: Dog: 86%, Horse: 86%, Human: 100%, Rabbit: 79%

Attributs du produit: This is a rabbit polyclonal antibody against EZR-ROS1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human ROS1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63796-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ROS1

Antigène: ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))

Autre désignation: ROS1

Sujet:

Background Information: This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor.

Gene Name: ROS proto-oncogene 1 , receptor tyrosine kinase

Alternative Symbols: ROS, MCF3, c-ros-1

Protein Name: proto-oncogene tyrosine-protein kinase ROS

Poids moléculaire: 94kDa

ID gène: 6098

NCBI Accession: NP_002935

UniProt: P08922

Pathways: Signalisation RTK