Integrin Alpha2b anticorps (N-Term)
Aperçu rapide pour Integrin Alpha2b anticorps (N-Term) (ABIN2789680)
Antigène
Voir toutes Integrin Alpha2b (CD41) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- ITGA2B Antibody - N-terminal region
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Séquence
- QGLGASVVSW SDVIVACAPW QHWNVLEKTE EAEKTPVGSC FLAQPESGRR
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Homologie
- Dog: 100%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 85%, Rat: 92%, Yeast: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against ITGA2B. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63955-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Integrin Alpha2b (CD41)
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Autre désignation
- ITGA2B
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Sujet
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Background Information: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Gene Name: Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Alternative Symbols: GT, GTA, CD41, GP2B, HPA3, CD41B, GPIIb, BDPLT2, BDPLT16, PPP1R93
Protein Name: Integrin alpha-IIb
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Poids moléculaire
- 16kDa
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ID gène
- 3674
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NCBI Accession
- NP_000410
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UniProt
- P08514
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Pathways
- Integrin Complex
Antigène
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