Integrin Alpha2b anticorps (N-Term)

N° du produit ABIN2789680

Détail du produit anti-Integrin Alpha2b anticorps

Antigène: Integrin Alpha2b (CD41)

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Porc, Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Integrin Alpha2b est non-conjugé

Application: Western Blotting (WB)

Séquence: QGLGASVVSW SDVIVACAPW QHWNVLEKTE EAEKTPVGSC FLAQPESGRR

Homologie: Dog: 100%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 85%, Rat: 92%, Yeast: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ITGA2B. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1039 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Integrin Alpha2b

Antigène: Integrin Alpha2b (CD41)

Autre désignation: ITGA2B (CD41 Produits)

Synonymes: anticorps AI172977, anticorps CD41, anticorps CD41B, anticorps GpIIb, anticorps alphaIIb, anticorps BDPLT16, anticorps BDPLT2, anticorps GP2B, anticorps GPIIb, anticorps GT, anticorps GTA, anticorps HPA3, anticorps integrin alpha 2b, anticorps integrin subunit alpha 2b, anticorps Itga2b, anticorps ITGA2B

Sujet: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Alias Symbols: CD41, CD41B, GP2B, GPIIb, GTA, HPA3, GT, BDPLT2
Protein Interaction Partner: FBXO6, PRKACA, CAMK2A, ITGA2B, AUP1, CIB1, CLNS1A, VWF, TLN1, F2, CD36, ITGB3, FGA, COL1A2, COL2A1, CALR, GRB2, RNF181,
Protein Size: 1039

Poids moléculaire: 16 kDa

ID gène: 3674

NCBI Accession: NM_000419, NP_000410

UniProt: P08514

Pathways: Integrin Complex