GPBAR1 anticorps (C-Term)

N° du produit ABIN2789752

L’anticorps anti-GPBAR1 Polyclonal Lapin est utilisé pour la détection de GPBAR1 dans des échantillons de Humain et Rat. Il a été validé pour WB.

Aperçu rapide pour GPBAR1 anticorps (C-Term) (ABIN2789752)

Antigène: GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPBAR1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GPBAR1 anticorps

Épitope: C-Term

Fonction: GPBAR1 Antibody - C-terminal region

Séquence: AAAVPVAMGL GDQRYTAPWR AAAQRCLQGL WGRASRDSPG PSIAYHPSSQ

Homologie: Human: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GPBAR1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64154-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur GPBAR1

Antigène: GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))

Autre désignation: GPBAR1

Sujet:

Background Information: This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.

Gene Name: G protein-coupled bile acid receptor 1

Alternative Symbols: BG37, TGR5, M-BAR, GPCR19, GPR131

Protein Name: G-protein coupled bile acid receptor 1

Poids moléculaire: 35kDa

ID gène: 151306

NCBI Accession: NP_733800

UniProt: Q8TDU6

Pathways: Signalisation WNT, Hormone Transport, Sensory Perception of Sound