KRT6A anticorps (Middle Region)
Aperçu rapide pour KRT6A anticorps (Middle Region) (ABIN2789833)
Antigène
Voir toutes KRT6A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- KRT6A Antibody - middle region
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Séquence
- RGMQDLVEDF KNKYEDEINK RTAAENEFVT LKKDVDAAYM NKVELQAKAD
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Homologie
- Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against KRT6A. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64419-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- KRT6A (Keratin 6A (KRT6A))
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Autre désignation
- KRT6A
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Sujet
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Background Information: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Gene Name: Keratin 6A
Alternative Symbols: K6A, K6C, K6D, PC3, CK6A, CK6C, CK6D, CK-6C, CK-6E, KRT6C, KRT6D
Protein Name: Keratin, type II cytoskeletal 6A
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Poids moléculaire
- 59kDa
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ID gène
- 3853
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NCBI Accession
- NP_005545
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UniProt
- P02538
Antigène
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