CFHR5 anticorps (N-Term)

N° du produit ABIN2790204

Détail du produit anti-CFHR5 anticorps

Antigène: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CFHR5 est non-conjugé

Application: Western Blotting (WB)

Séquence: SCVERGWSTP PICSFTKGEC HVPILEANVD AQPKKESYKV GDVLKFSCRK

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CFHR5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CFHR5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 569 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CFHR5

Antigène: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Autre désignation: CFHR5 (CFHR5 Produits)

Synonymes: anticorps CFHL5, anticorps CFHR5D, anticorps FHR-5, anticorps FHR5, anticorps complement factor H related 5, anticorps CFHR5

Sujet: This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein.
Alias Symbols: CFHL5, FHR-5, FHR5, FLJ10549, MGC133240
Protein Interaction Partner: C3,
Protein Size: 569

Poids moléculaire: 64 kDa

ID gène: 81494

NCBI Accession: NM_030787, NP_110414

UniProt: Q9BXR6