FOXO4 anticorps (Middle Region)
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- Antigène Voir toutes FOXO4 Anticorps
- FOXO4 (Forkhead Box O4 (FOXO4))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Porc, Cheval, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FOXO4 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- YLYQILQGIV FCHSRRVLHR DLKPQNLLID DKGTIKLADF GLARAFGIPI
- Homologie
- Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against FOXO4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human FOXO4
- Top Product
- Discover our top product FOXO4 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 505 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- FOXO4 (Forkhead Box O4 (FOXO4))
- Autre désignation
- FOXO4 (FOXO4 Produits)
- Synonymes
- anticorps FOXO4, anticorps foxo4, anticorps AFX, anticorps AFX1, anticorps MLLT7, anticorps Afxh, anticorps Mllt7, anticorps afx, anticorps RGD1561201, anticorps forkhead box O4, anticorps forkhead box O4 L homeolog, anticorps FOXO4, anticorps foxo4.L, anticorps Foxo4
- Sujet
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FOXO4 is transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. The protein can down-regulate expression of HIF1A and suppress hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias.
Alias Symbols: AFX, AFX1, MGC120490, MLLT7
Protein Interaction Partner: REL, SFN, AKT1, OGT, UBC, ATXN3, MDM2, NLK, USP7, CTNNB1, CREBBP, VDR, SIRT1, SMAD3, XPO1, YWHAZ, SMAD4, FOXG1, AKT2, ESR1, PIN1, CCND1, CDKN1A,
Protein Size: 505 - Poids moléculaire
- 54 kDa
- ID gène
- 4303
- NCBI Accession
- NM_005938, NP_005929
- UniProt
- P98177
- Pathways
- Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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