DIABLO anticorps (C-Term)

N° du produit ABIN2792127

Cet anticorps Lapin Polyclonal détecte spécifiquement DIABLO dans WB et IHC. Il présente une réactivité envers Humain, Boeuf (Vache), Chien, Cheval et Porc.

Aperçu rapide pour DIABLO anticorps (C-Term) (ABIN2792127)

Antigène: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Reactivité: Humain, Boeuf (Vache), Chien, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DIABLO est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-DIABLO anticorps

Épitope: C-Term

Séquence: LVKLQVEEVH QLSRKAETKL AEAQIEELRQ KTQEEGEERA ESEQEAYLRE

Homologie: Cow: 85%, Dog: 92%, Horse: 85%, Human: 100%, Pig: 85%

Attributs du produit: This is a rabbit polyclonal antibody against DIABLO. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human DIABLO

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 186 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DIABLO

Antigène: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Autre désignation: DIABLO

Sujet: DIABLO is an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Several alternatively spliced transcript variants that encode distinct isoforms have been described for this gene but the validity of some transcripts, and their predicted ORFs, has not been determined conclusively.
Alias Symbols: SMAC, SMAC3, DFNA64, DIABLO-S
Protein Interaction Partner: BIRC7, ARL6IP1, UBC, XIAP, BIRC2, BIRC6, BIRC3, MDM2, GABPA, AP1B1, SSRP1, ABCE1, GMPPB, LIMCH1, BMH1, AREL1, SLC25A47, MAML2, UBL4A, NR4A1, ARNT, MALT1, BIRC8, HTRA2, CDC40, DIABLO, ELAVL1, UBE2K, ZNF746, TOLLIP, UFM1, TRAF2, TRAF1, EEF1A1, Ngfrap1, BIRC
Protein Size: 186

Poids moléculaire: 21 kDa

ID gène: 56616

NCBI Accession: NM_138930, NP_620308

UniProt: Q502X2

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity