Cyclin G1 anticorps (N-Term)
Aperçu rapide pour Cyclin G1 anticorps (N-Term) (ABIN2792152)
Antigène
Voir toutes Cyclin G1 (CCNG1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- IEVLTTTDSQ KLLHQLNALL EQESRCQPKV CGLRLIESAH DNGLRMTARL
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Homologie
- Cow: 100%, Dog: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rat: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against CCNG1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human CCNG1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 295 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Cyclin G1 (CCNG1)
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Autre désignation
- CCNG1
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Sujet
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The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. CCNG1 is a member of the cyclin family and contains the cyclin box. It lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene.The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: CCNG
Protein Interaction Partner: KRTAP10-7, SPERT, KRT40, LZTS2, HMBOX1, PAK7, TFIP11, RBPMS, TNIP1, PNMA1, SHKBP1, PLEKHA4, TFAP2C, NFATC4, LTBP3, GRN, APP, UBC, CDK2, TP73, TP53, PPP2CA, GAK, PPP2R4, CDKN2A, COX2, MDM2, CDK5,
Protein Size: 295 -
Poids moléculaire
- 34 kDa
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ID gène
- 900
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NCBI Accession
- NM_004060, NP_004051
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UniProt
- P51959
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Pathways
- Signalisation p53
Antigène
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