CDK7 anticorps (C-Term)

N° du produit ABIN2792153

Cet anticorps Lapin Polyclonal détecte spécifiquement CDK7 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Chien et Cobaye.

Aperçu rapide pour CDK7 anticorps (C-Term) (ABIN2792153)

Antigène: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CDK7 anticorps

Épitope: C-Term

Séquence: NRPGPTPGCQ LPRPNCPVET LKEQSNPALA IKRKRTEALE QGGLPKKLIF

Homologie: Cow: 100%, Dog: 94%, Guinea Pig: 94%, Horse: 100%, Human: 100%, Mouse: 88%, Pig: 100%, Rat: 88%

Attributs du produit: This is a rabbit polyclonal antibody against CDK7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CDK7

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 346 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CDK7

Antigène: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Autre désignation: CDK7

Sujet: Cdk7 is the catalytic subunit of the CDK-activating kinase (CAK) complex, a serine-threonine kinase. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcripti
Alias Symbols: CAK1, CDKN7, MO15, STK1, p39MO15, HCAK
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, GTF2H4, GTF2H3, GTF2H2, GTF2H1, ERCC5, ERCC3, ERCC2, CDK7, CCNH, ATP2B4, A2M, GTF2H5, SRPK2, SRPK1, MNAT1, TP53, CDK2, CTD, MBP, CDK1, CCNB1, CCNA2, Dlg4, UVSSA, HSP90AA1, HSD17B4, HLA-DQA1, SUPT5H, POLR2A, GTF2E2, GTF2E1, CDK9, APP
Protein Size: 346

Poids moléculaire: 39 kDa

ID gène: 1022

NCBI Accession: NM_001799, NP_001790

UniProt: P50613

Pathways: Cycle Cellulaire, Réparation de l'ADN, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase