CDC25A anticorps (Middle Region)

N° du produit ABIN2792169

L’anticorps anti-CDC25A Polyclonal Lapin est utilisé pour la détection de CDC25A dans des échantillons de Humain, Souris, Rat, Chien, Cheval, Lapin et Cobaye. Il a été validé pour WB.

Aperçu rapide pour CDC25A anticorps (Middle Region) (ABIN2792169)

Antigène: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC25A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CDC25A anticorps

Épitope: Middle Region

Fonction: CDC25A Antibody - middle region

Séquence: MELCEPQSYC PMHHQDHKTE LLRCRSQSKV QEGERQLREQ IALLVKDMSP

Homologie: Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CDC25A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CDC25A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CDC25A

Antigène: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Autre désignation: CDC25A

Sujet:

Background Information: CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Cell division cycle 25 homolog A (S. pombe)

Alternative Symbols: CDC25A2

Protein Name: M-phase inducer phosphatase 1

Poids moléculaire: 54kDa

ID gène: 993

NCBI Accession: NP_963861

UniProt: P30304

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase