c-FOS anticorps (N-Term)

N° du produit ABIN2792182

Cet anticorps anti-c-FOS est un anticorps Lapin Polyclonal détectant c-FOS dans WB et IHC. Adapté pour Humain, Rat, Souris, Boeuf (Vache), Porc, Chien et Mouton.

Aperçu rapide pour c-FOS anticorps (N-Term) (ABIN2792182)

Antigène: c-FOS (c-Fos) (c-Fos)

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Porc, Chien, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp c-FOS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-c-FOS anticorps

Épitope: N-Term

Séquence: MFSGFNADYE ASSSRCSSAS PAGDSLSYYH SPADSFSSMG SPVNAQDFCT

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against FOS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FOS

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 380 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur c-FOS

Antigène: c-FOS (c-Fos) (c-Fos)

Autre désignation: FOS

Sujet: The Fos family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The family members are leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: c-fos, p55, AP-1, C-FOS
Protein Interaction Partner: Psma4, CENPO, LMO3, ARFGAP1, USF2, USF1, PSMC5, PRKAA2, JUNB, JUN, GNG11, NQO1, ATF2, AQP1, LUZP4, CYTH4, CREB5, ABL1, CLU, ATP5I, APP, MTERF4, ANP32E, ARL6IP4, COPS4, CABP1, ZNF133, SET, NEFM, MAP1B, JUND, HSPA1A, MAF, FOS, DDIT3, CEBPG, CEBPE, CEBPA, AT
Protein Size: 380

Poids moléculaire: 41 kDa

ID gène: 2353

NCBI Accession: NM_005252, NP_005243

UniProt: P01100

Pathways: S100 Proteins